BMG LABTECH is a leading developer and manufacturer of microplate reader instrumentation for high-throughput screening, as well as for other life science applications in academic and pharmaceutical research.
Gold-standard for HTS microplate readers
If you’re looking for the fastest, most sensitive microplate reader, consider the PHERAstar FS. The PHERAstar FS is the ultimate multimode microplate reader for HTS labs, core / academic facilities, and assay development. Based on the highly successful PHERAstar Plus platform, while having many unique features that separate it from its predecessor, the PHERAstar FS is capable of performing assays not possible on other microplate readers.
It has BMG LABTECH’s unique Tandem Technology, an ultra-fast UV/Vis spectrometer (220nm-1,000nm) for absorbance measurements and highly sensitive, filter-based detection for other modes, which include fluorescence intensity, FRET, fluorescence polarization, time-resolved fluorescence, TR-FRET UV/Vis absorbance, AlphaScreen®, and luminescence.
Proprietary technology greatly enhances many applications, including: two dedicated lasers for AlphaScreen® and TR-FRET based assays; specialized dual emission optics for 3456-well microplate capability; on-board reagent injectors for precise kinetic assays; and advanced direct optic bottom reading for cell-based assays. Furthermore, the PHERAstar FS is optimized for the most demanding HTS assays including HTRF®, LanthaScreen®, Transcreener®, LANCE®, DELFIA®, GeneBLAzer®, AlphaScreen®, and BRET.
Absorbance reader with an ultra-fast CCD spectrometer
Using microplates, cuvettes, or low volume samples, the SPECTROstar Nano is capable of measuring full absorbance spectra (220nm – 1,000nm) at resolutions down to 1nm in less than one second per well. With BMG LABTECH’s proprietary CCD-based spectrometer, full spectrum absorbance measurements can be taken as quickly as a single wavelength.
Fast, full spectrum analysis provides measurement possibilities that were not before possible and it can improve all assays, including ELISAs, DNA/RNA quantification, and enzyme kinetics. Able to measure all microplates up to 1536-wells, standard cuvettes, and low volume samples using the LVis low volume plate, the SPECTROstar Nano is the perfect absorbance microplate reader for any laboratory.
Multimode microplate reader with a CCD spectrometer
The Omega series of life science microplate readers is the first line of multimode microplate readers with Tandem Technology, which entails using a spectrometer for absorbance and filters for other detection modes. Having a proprietary CCD-based spectrometer, a full absorbance spectrum (220nm – 1,000nm) can be captured at a resolution of 1nm in less than 1 second per well. This is at least ten times faster and at a ten times higher resolution than the fastest monochromator-based instrument.
Capable of using all microplate formats up to 1536-well, the Omega line is comprised of the SPECTROstar Omega, a spectrophotometer; the LUMIstar Omega, a luminometer; the FLUOstar Omega, a multi-detection microplate reader (fluorescence intensity, time-resolved fluorescence, TR-FRET [including HTRF® and LanthaScreen®], AlphaScreen®, high-performance luminescence, and UV/Vis absorbance); and the POLARstar Omega, a multi-detection plate reader with simultaneous dual emission (SDE) and fluorescence polarization detection mode.
Due to the absolute modular concept, the SPECTROstar Omega, LUMIstar Omega and FLUOstar Omega are entirely upgradeable to include additional measurement modes when the need arrives.
Upgradable multimode microplate readers
If you are searching for a sensitive, flexible, proven microplate reader with kinetic capabilities at a great price, the OPTIMA microplate reader is the optimal solution for academic and pharmaceutical research. The FLUOstar OPTIMA multimode microplate reader offers four measurement modes: fluorescence, time-resolved fluorescence, luminescence, and absorbance. It can also be upgraded to the POLARstar OPTIMA with fluorescence polarization and simultaneous dual emission for FRET and BRET applications. The LUMIstar OPTIMA is a fully upgradeable luminometer for flash and glow type luminescence assays.
All OPTIMA microplate readers can be equipped with top and bottom reading, incubation, shaking, and two on-board reagent injectors for kinetic assays such as DLR®.
Light-scattering microplate nephelometer for solubility screening
Offering a rapid method to test drug/compound solubility, bacterial and fungal growth, macromolecule quantification, and immunocomplex formation, the NEPHELOstar Plus measures forward scattered light of turbid samples in a microplate format. The NEPHELOstar Plus is the world’s only laser-based nephelometer, out-performing halogen lamp-based units both in sensitivity and reproducibility.
High-performance microplate reader with advanced LVF monochromators, spectrometer and filters
The CLARIOstar is a multimode microplate reader with new advanced LVF monochromators, highly sensitive filters, and an ultra-fast spectrometer.
The CLARIOstar is a modular microplate reader with all major detection modes:
- Fluorescence intensity
- FRET
- Fluorescence polarisation
- Time-resolved fluorescence
- TR-FRET
- Luminescence
- BRET
- UV / Vis absorbance
- AlphaScreen® /AphaLISA®
Advanced LVF monochromators and filter selector system
Perfect for measuring and developing fluorescence assays, the CLARIOstar has advanced LVF monochromators for flexibility that can be used in combination with filters for greater sensitivity. The advanced LVF monochromators, having continually adjustable wavelengths (320nm to 850nm) and bandwidths (8nm to 100nm) for excitation and emission, have significantly increased performance over conventional monochromators giving them filter-like performance.
As well as continually adjustable bandwidths up to 100nm, BMG LABGTECH’s Advanced LVF Monochromators have several unique features that will enhance fluorescence and luminescence assays.
As mentioned, the LVF monochromators can be used in combination with filters in the same measurement test, filters can be used for excitation while the LVF monochromators can be used for emission, or vice versa. In addition, highly sensitive emission scanning in both fluorescence and luminescence assays can be performed at concentrations lower than conventional monochromators.
Technology for enhancing science assays
In addition to its advanced LVF monochromators for fluorescence and luminescence assays, the CLARIOstar has technology that enhances other life science assays. Rapid, full spectrum UV/Vis absorbance (220nm to 1,000nm) is performed with BMG LABTECH’s proprietary ultra-fast spectrometer (<1 sec/well).
AlphaScreen® and AlphaLISA® measurements are improved with a dedicated, high energy Laser. Kinetic and cell-based assays can be initiated with precise reagent injectors. While an integrated fluorophore library in the control software simplifies assay development and assay set up.