PHARMATRANS SANAQ specialises in innovative and multifunctional excpients for solid dosage forms as well as in value added APIs for pharmaceuticals. As a partner for the pharmaceutical industry, we have been working in this field for over 25 years. Our aim is to provide the industry with customised products and solutions. We continuously search and develop new excipients, or better forms of existing excipients, based on the needs of our partners in the industry.
MCC SANAQburst – multifunctional excipient as binder, filler and superdisintegrant
MCC SANAQburst consists of 100% pure microcrystalline cellulose (no additional excipients). The fast disintegration remains even after wet granulation and extrusion processes. With MCC SANAQburst reduction of excipients in a formulation can be achieved, fast disintegration tablets, dispersible and ODTs as well as fast dissolving pellets by extrusion / spheronisation.
Microcrystalline cellulose pellets – neutral starter core
CELLETS microcrystalline cellulose pellets are a neutral starter of 100% microcrystalline cellulose. As inert carriers, CELLETS are mainly used for controlled release formulations and for innovative drug delivery, already being available from below 100µm. The product characteristics lead to a reproducible and reliable production process.
The advantages of CELLETS include:
- The wide range of particle size fractions with uniform spherical shape and structure (100µm – 1,400µm)
- Narrow particle size distribution within each fraction
- Formulation of sensitive actives, due to the inertness of MCC
- High abrasion resistance, which improves the coating process
- Excellent compactability, due to the high plasticity of the CELLETS, for formulation of multidosage tablets
- Higher payload permits smaller capsule sizes
Carnauba Wax pellets as hydrophobic, neutral starter core
C-Wax Pellets constist of 100% Carnauba Wax. In some formulations a hydrophobic core is needed to achieve a specific dissolution profile. C-Wax Pellets do not require an additional subcoating to achieve this effect and other starter cores.
Sugar Spheres as neutral starter core
Sugar Spheres Sanaq are sugar non-pareils – neutral starter cores for the production of controlled release formulations or for direct compression to ensure the content uniformity of low dosage API in tablets.
Mannitol pellets as neutral starter core
MCELL consist of 100% Mannitol and are non-hygroscopic, highly spherical, dense and have a low attrion to be used as alternative water soluble starter core for pellet formulations.
Tartaric Acid pellets as functional starter core
TAP are spherical cores and consist of 100% Tartaric Acid. TAP act as a pH-modifier for substances (e.g. weakly basic drugs) with a poor solubility in higher pH that occur in the lower GIT. TAP enhance the solubility in this environment.
- TAP 200: 100-350 micron
- TAP 400: 300-500 micron
- TAP 500: 400-600 micron
Microcrystalline cellulose
Microcrystalline cellulose MCC SANAQ is a purified and partially depolymerised a-cellulose widely used as filler, binder and granulation aid for tablets, granules and in capsules. Different types for wet granulation, dry granulation and direct compression are available – MCC SANAQ 101L, 102L, 200L, 301L, 302L.
MCC SANAQ UL-002 compactible binder
MCC SANAQ UL-002 is a highly compactible binder. Thanks to its low bulk density and different particle shape, the compactablity is significantly enhanced compared to standard MCC types. This leads to lower compression forces in case of pressure sensitive formulations and higher drug loading (or smaller sized tablets with the same drug loading) thanks to the reduction of excipient. The product portfolio also includes:
Sodium starch glycolate superdisintegrant
SSG SANAQ is a super disintegrant for tablets, capsules and granules.
Sodium stearyl fumarate lubricant
LubriSanaq is a high-quality lubricant for tablet and capsule formulations.
100% Ibuprofen pellets for direct compression
Ibuprofen DC 100 is an optimised Ibuprofen to perform high-speed tableting processes, overcoming sticking and picking behaviour.
Acetylsalicylic acid solvent-free coated
ASACOAT SANAQ is a lipid coated acetylsalicylic acid to enhance the stability of the API by moisture protection.