Research carried out by scientists at John Hopkins University have hypothesised and studied why Covid-19 might be causing a loss of sense of smell, or ansosmia, in some patients.
The researchers found that the ACE2 protein, which is the mechanism of cellular entry for SARS-CoV-2, the virus that causes Covid-19, is “expressed at high levels in the human olfactory epithelium” inside the nasal cavity and involved in smell.
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The John Hopkins team believe that these findings also suggest than an intranasal administration of anti-viral drugs could be an effective Covid-19 treatment approach.
The research was published in the European Respiratory journal and supported by funding from the US National Institutes of Health.
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