Genus Oncology has dosed the first patient in a Phase I trial to evaluate its GO-203-2c compound as a treatment for solid tumours.

The prospective, open-label trial is designed to determine the safety, tolerability and potential anti-tumour activity of GO-203-2c.

Up to 40 patients will be enrolled at multiple clinical sites.

GO-203-2c is the optimised lead peptide drug candidate, synthesised to target MUC1, an oncoprotein that is over-expressed in many human carcinomas.

Genus has also filed an investigational new drug application with the US Food & Drug Administration.

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