Daily Newsletter

07 September 2023

Daily Newsletter

07 September 2023

Signal: Nimbus raises $210m to foster drug discovery plans

Nimbus plans to use these funds to aid new drug discovery efforts and plans to continue existing programs in oncology and metabolic disorder.

Manasi Vaidya September 07 2023

Nimbus Therapeutics has closed a $210m fundraising round involving existing and new investors, notably GV or Google Ventures. This comes more than six months since Nimbus closed a high-profile deal with Takeda Pharmaceuticals where the latter acquired a subsidiary in a deal that holds the potential to yield multi-billion dollar milestone-based payments.

Over the years, Nimbus has accrued an impressive list of private investors and venture capital. In a $125 million round announced in September 2022, Bain Capital and SV Health investors joined existing investors, which include Atlas Venture, Bill Gates, Pfizer Ventures, RA Capital Management, amongst others, as per GlobalData's Deals database.

GlobalData is the parent company of Pharmaceutical Technology.

GV featured as a new investor in the latest round. Dr. Krishna Yeshwant, general partner at GV, highlighted the company’s expertise in “integrating cutting-edge computational chemistry, high-tech structural biology tools and other industry-shaping technologies and approaches” in the announcement accompanying the fundraise.

Nimbus relies on a computational chemistry-led platform to exploit protein structure data and identify potential drug targets. As per the company, the differentiating factor here is its interdisciplinary work across biophysics, protein discover, enzymology and screening. The latest financing is supposed to aid the development of other programs that target enzyme and autoimmune disorders in preclinical and clinical stages.

As part of the deal that closed in February, Takeda acquired NDI-034858 a tyrosine kinase 2 (TYK2) inhibitor being developed for several autoimmune diseases. As per GlobalData, the acquisition aligned well with Takeda’s expertise in immune-mediated diseases, and added to its late-stage pipeline. NDI-034858 is currently in Phase II clinical trials.

Our signals coverage is powered by GlobalData’s Thematic Engine, which tags millions of data items across six alternative datasets — patents, jobs, deals, company filings, social media mentions and news — to themes, sectors and companies. These signals enhance our predictive capabilities, helping us to identify the most disruptive threats across each of the sectors we cover and the companies best placed to succeed. 

M&A in the Contract Manufacturing Industry

Despite challenging business conditions in 2021 and 2022, large CMOs were still involved in acquisitions to enhance their capabilities or scale of production. Catalent and Recipharm were particularly active in acquiring companies during this period, and these acquisitions had a focus on advanced biologic capabilities related to cell and gene therapies. CMOs are increasingly targeting companies with sophisticated (biologic and specialized) capabilities to manufacture modern drugs and seek high-value contracts.

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