Daily Newsletter

28 September 2023

Daily Newsletter

28 September 2023

Ono and Adimab partner to develop oncology antibody drugs

Adimab will receive an upfront payment, research and development funding, and success-based milestone payments from Ono.

RanjithKumar Dharma September 28 2023

Ono Pharmaceutical and Adimab have signed a drug discovery collaboration agreement for the development of antibody drugs in the oncology segment.

Adimab will be responsible for the discovery of new therapeutic antibodies for Ono’s multiple targets. It will also create bispecific antibody product candidates.

Ono will assess and develop those candidates at the pre-clinical and clinical stages.

The company will have the option to receive exclusive rights for the global development, manufacturing and commercialisation of the candidates generated through the partnership.

Ono discovery and research senior executive officer and executive director Dr Toichi Takino stated: “We are actively working to create biologics like antibodies in order to address unmet medical needs for a wide range of diseases, including cancers.

“We are very pleased to collaborate with Adimab this time in the oncology area and expect that their multi-specific antibody engineering technologies will create potential novel bispecific antibody candidates.”

Adimab will receive an upfront payment, research and development funding, and success-based milestones from Ono on research, clinical development and regulatory progress, and tiered royalties based on net sales.

Adimab chief business officer Guy Van Meter stated: “We are very pleased to be able to partner with Ono Pharmaceuticals based on our technology in antibody discovery and bispecific antibody generation. Adimab has more than 105 partners across the world, and we are thrilled to add Ono to our partners' list.”

M&A in the Contract Manufacturing Industry

Despite challenging business conditions in 2021 and 2022, large CMOs were still involved in acquisitions to enhance their capabilities or scale of production. Catalent and Recipharm were particularly active in acquiring companies during this period, and these acquisitions had a focus on advanced biologic capabilities related to cell and gene therapies. CMOs are increasingly targeting companies with sophisticated (biologic and specialized) capabilities to manufacture modern drugs and seek high-value contracts.

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