Daily Newsletter

12 October 2023

Daily Newsletter

12 October 2023

Astellas, BioLabs and Mitsui collaborate for Japanese life sciences hub

The collaboration aims to boost open innovation hub SakuLab-Tsukaba at Astellas’ Tsukuba Research Centre.

Jenna Philpott October 11 2023

Astellas Pharma, BioLabs Global and Mitsui Fudosan have entered into a memorandum of understanding to strengthen the life sciences sector in Tsukuba, Kashiwa-no-ha and the surrounding areas of Japan.

The Sakulab-Tsukaba lab, located at Astellas’ Tsukuba research centre, provides support for startups and academia in the research and development of small molecule drugs, antibody drugs, gene and cell therapy, and other areas.

BioLabs will be supporting Astellas by assisting with facility management and co-hosting networking events for residents and connect them to the global life science ecosystem.

Astellas’ chief scientific officer Yoshitsugu Shitaka said: “With this agreement, we envision our labs in Tsukuba and Kashiwa-no-ha to be where visionary ideas and specialised knowledge converge, turbocharging the development of development of pioneering healthcare solutions.”

Astellas has entered into several research agreements this year. The company signed a joint research agreement with Veneno Technologies in April for the development of functional peptides, and signed a licence deal with Kate Therapeutics to develop and commercialise its X-linked myotubular myopathy (XLMTM) gene therapy, KT430 in June.

In June, Astellas and Mitsui Fudosan entered a partnership where Astellas opened the TME iLab open innovation hub in Mitsui Fudosan’s Mitsui Link-lab Kashiwa-no-ha-1, for research of the tumour microenvironment. This partnership will strengthen Kashiwa-no-ha’s role in the life sciences sector.

Last month, Astellas submitted a planning application for the construction of a new drug production facility in Ireland, in a €330m ($350m) investment.

Significant opportunities and risks for disease-modifying therapies (DMTs) entering the PD market

As PD therapy currently centers on symptomatic treatment, the need for DMTs is one of the greatest unmet needs. Several companies within the late-stage PD pipeline are developing drugs that target PD via novel MOAs. KOLs remain hopeful that these companies will uncover a class of drugs that works effectively to slow or modify the disease course. Targeting α-synuclein and other neurotoxic proteins is a key strategy in the late-stage pipeline for DMTs.

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