CAR-T therapies and cancer risk: No easy answers for the FDA
CAR-T cell therapies can provide durable cancer remission, however, a recent FDA investigation into reports of secondary T-cell malignancies has increased scrutiny of their risk profiles.
29 January 2024
29 January 2024
CAR-T cell therapies can provide durable cancer remission, however, a recent FDA investigation into reports of secondary T-cell malignancies has increased scrutiny of their risk profiles.
Type-2 diabetes patients continue to be impacted by GLP-1 RA drug shortages in the UK with an NHS alert issuing guidelines on drug substitutions.
Regeneron and Sanofi’s blockbuster anti-inflammatory drug generated global sales of $8.68bn in 2022.
Developed by Bristol Myers Squibb (BMS), Abecma showed significant improvement in progression-free survival for multiple myeloma patients in a Phase III clinical trial.
MSD will supply Keytruda to be evaluated as a combination treatment with Lava’s LAVA-1207 in an ongoing Phase I/IIa study.
ENHERTU is intended for the treatment of HER2-positive solid tumours.
The BLA for CT-P47 is supported by data from an international Phase III clinical trial.
Renalys plans to start a registrational trial for sparsentan as a treatment for IgA nephropathy in Japan in the second quarter (Q2) of 2024.
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