Share
Sanofi will make an upfront payment of $40m to Scribe Therapeutics. Credit: nitpicker / Shutterstock.com.

Scribe Therapeutics and Sanofi have expanded their partnership to progress the development of in vivo genetic therapies to treat sickle cell and other genomic diseases.

Sanofi will obtain an exclusive licence for the usage of the CRISPR X-Editing (XE) genome editing technologies of Scribe to develop in vivo therapies.

Related Company Profiles

View all

The latest in vivo partnership will use CRISPR XE, along with Sanofi’s expertise in non-viral delivery, towards an initial target of treating sickle cell disease. 

Sanofi will make an upfront payment of $40m to Scribe, followed by milestone payments of $1.2bn on meeting specific development and sales goals and royalty payments on future net product sales resulting from the deal. 

Scribe also holds the right to choose to share development expenses and activities. This will include joint promotion and the splitting of profit and loss in the US on one future programme.

The parties entered a partnership to develop cell therapies for treating cancer in September 2022.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

Scribe Therapeutics co-founder and CEO Benjamin Oakes stated: “We are continually impressed by the expertise, rigour and urgency that Sanofi has brought to our existing ex vivo collaboration, as well as their rapid advancements and innovation in non-viral delivery technologies. Now, we are thrilled to expand our work together into new areas of high unmet need. 

“This in vivo collaboration further demonstrates the versatility of Scribe’s design-based approaches to CRISPR, which enable greater activity, specificity and deliverability, ultimately accelerating the development of life-changing therapeutics.”

Cell & Gene Therapy coverage on Pharmaceutical Technology is supported by Cytiva.

Editorial content is independently produced and follows the highest standards of journalistic integrity. Topic sponsors are not involved in the creation of editorial content.