The Israel Ministry of Health (MOH), Pfizer and BioNTech have reported real-world evidence showing significantly reduced incidence rates of Covid-19 in fully vaccinated people.
The Pfizer-BioNTech Covid-19 Vaccine (BNT162b2) is based on the latter’s mRNA technology and authorised for emergency use in over 60 countries.
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By GlobalDataThe latest data build upon and reinforce earlier evidence from the MOH showing the vaccine’s effectiveness in preventing symptomatic SARS-CoV-2 infections, Covid-19 cases, hospitalisations, severe and critical hospitalisations and deaths.
According to the latest information, protection is more robust two weeks after the second vaccine dose. Also, the vaccine showed at least 97% effectiveness in preventing symptomatic disease, severe and critical disease and death.
In addition, the analysis showed a 94% vaccine effectiveness against asymptomatic disease.
Pfizer noted that this real-world evidence could be important to all nations as they advance their inoculation campaigns a year after the World Health Organization (WHO) declared Covid-19 a pandemic.
MOH director professor Yeheskel Levy said: “Incidence rates in the fully vaccinated population have massively dropped compared to the unvaccinated population, showing a marked decline in hospitalised cases due to Covid-19.
“This clearly demonstrates the power of the Covid-19 vaccine to fight this virus and encourages us to continue even more intensively with our vaccination campaign.”
The findings were derived from de-identified aggregate Israel MOH surveillance data obtained between 17 January and 6 March.
During this time, the Pfizer-BioNTech vaccine was the only vaccine in the country and the highly infectious B.1.1.7 variant of SARS-CoV-2 (the UK variant) was the dominant strain.
Pfizer Vaccines senior vice-president and chief medical officer Luis Jodar said: “The findings, which suggest that the vaccine may also provide protection against asymptomatic SARS-CoV-2 infections, are particularly meaningful as we look to disrupt the spread of the virus around the globe.”