German life science company Evotec has announced plans to shut down its gene therapy business as Q1 2024 group revenues are down by 2%. 

Evotec said it will exit the gene therapy business, shutting down Evotec GT, and will streamline focus on its ā€œcore modalities.ā€ As part of the restructuring, a site in Austria will be closed ā€“ a move that will affect 40 employees. The company ventured into the gene therapy arena in April 2020, when it teamed up with Takeda to utilise its gene therapy approaches. Ā 

As per its latest Q1 2024 financial report, group revenues decreased by 2% compared to the same period last year, excluding currency effects, to ā‚¬208.7m ($226.6m).  

This latest update comes after Evotec announced its FY 2023 financials on 24 April 2024. At that time, the companyā€™s shares dropped nearly 35% as it revealed a ā€œpriority resetā€ to its business plan. The company also announced new CEO Christian Wojczewski would be joining the company in July, replacing interim leader Mario Polywka. Ā 

Evotec said it will simplify its organisational structure and operating model while optimising footprint and capacity, aiming to lift earnings by at least ā‚¬40m per year. However, shares have failed to recover since the April announcement. 

Itā€™s been a tricky year for the company, following the sudden departure of former CEO Werner Lanthaler in January 2024. Lanthaler cited personal reasons for leaving, however, Evotec disclosed in a business call that the supervisory board agreed on termination with immediate effect following ā€œhis late disclosure of transactions in company sharesā€ made over three years. Evotec announced a US listing in November 2021.Ā 

However, Evotec has a positive business outlook for full year 2024, with chief financial officer Laetitia Rouxel saying in the 22 May announcement: ā€œThe strategic reset we announced last month has set us on a dynamic path back to sustainable profitable growth.ā€Ā 

Aside from this, Evotec has struck several deals since the start of the year. This includes a partnership with the Crohnā€™s & Colitis Foundation for irritable bowel disease therapies in January, and an agreement with Variant Bio aimed at detecting a treatment for ailments caused by fibrosis.Ā 

Most recently, Evotec teamed up with pharma giant Bayer to develop precision cardiology therapeutics. Evotecā€™s human-induced pluripotent stem cells will be used to develop new therapies. The financial terms of this agreement were not disclosed by either company. Ā