The company expects to start manufacturing of the intranasal vaccine candidate during the third quarter of this year. Credit: Willfried Wende from Pixabay.

Biopharmaceutical firm Altimmune has signed a teaming agreement with DynPort Vaccine to support US Government funding efforts for the development of its intranasal Covid-19 vaccine candidate, AdCOVID.

If successful, the partnership will be extended to programme management, drug development and regulatory support for the vaccine product.

Go deeper with GlobalData

Data Insights

The gold standard of business intelligence.

Find out more

Related Company Profiles

View all

DynPort has expertise in vaccine development and the preclinical, manufacturing, clinical and regulatory activities required for FDA licensure of new drug products.

Altimmune expects that the collaboration with DynPort will boost its capabilities to obtain and execute on US Government funding opportunities for developing AdCOVID.

Currently, the vaccine candidate is undergoing preclinical studies being performed in alliance with the University of Alabama at Birmingham (UAB). Initial data from these studies are expected to be available soon.

The company expects to start manufacturing of the intranasal vaccine candidate during the third quarter of this year, with a Phase I clinical trial planned for the fourth quarter.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

AdCOVID is designed to protect the respiratory tract from the virus, also intended to offer downstream protection against the viral spread by stimulating mucosal and systemic antibodies and cell-mediated immunity.

The ability to induce mucosal immunity in the nasal cavity, an entry and replication point for the SARS-CoV-2 virus, is expected to protect against the infection and also spread of the virus to others.

In addition, intranasal delivery could facilitate easier administration compared to injection.

Currently, Altimmune has two programmes with non-dilutive government funding.

One of the programmes is an intranasal anthrax vaccine candidate, NasoShield, being developed as part of a contract valued at approximately $133.7m with the Biomedical Advanced Research and Development Authority (BARDA).

The second programme is an intranasal therapeutic meant for early Covid-19, T-COVID, being developed under a $4.7m US Army Medical Research & Development Command (USAMRDC) contract.

Both programmes are based on the replication-deficient adenovirus 5 platform used for AdCOVID.