Zydus Lifesciences. has filed a patent for a liquid oral formulation containing 10 mg/mL of sildenafil citrate and glycerin as a wetting agent. The formulation is designed for the treatment of conditions like pulmonary arterial hypertension and erectile dysfunction. GlobalData’s report on Zydus Lifesciences gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on Zydus Lifesciences, NSAID cancer drugs was a key innovation area identified from patents. Zydus Lifesciences's grant share as of January 2024 was 32%. Grant share is based on the ratio of number of grants to total number of patents.
The patent application (Publication Number: US20230381187A1) discloses a ready-to-use liquid oral formulation containing sildenafil citrate at a concentration of about 10 mg/mL, along with pharmaceutically acceptable excipients including a wetting agent like glycerin. The formulation is specified to have a pH ranging from about 4 to 8, with variations in pH levels mentioned in specific claims. Additionally, the formulation may include a buffering agent and anti-foaming agent, along with sildenafil citrate particles and a viscosity-modifying agent comprising water-soluble hydrocolloids.
Furthermore, the patent application outlines methods of treating various conditions in humans by administering the disclosed liquid oral formulation. The conditions mentioned include hypertension, pulmonary hypertension, arterial hypertension, pulmonary arterial hypertension, and erectile dysfunction. The stability of the formulation is highlighted, indicating that it remains stable for up to six months when stored under specific conditions. The presence of impurities in the composition is also limited to ensure product quality and efficacy in treating the specified conditions.
To know more about GlobalData’s detailed insights on Zydus Lifesciences, buy the report here.
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