VTX-2735 is under clinical development by Ventyx Biosciences and currently in Phase II for Familial Cold Autoinflammatory Syndrome (Familial Cold Urticaria). According to GlobalData, Phase II drugs for Familial Cold Autoinflammatory Syndrome (Familial Cold Urticaria) have a 67% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how VTX-2735’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

VTX-2735 overview

VTX-2735 is under development for the treatment of systemic inflammatory diseases, recurrent pericarditis, cryopyrin-associated periodic syndrome (CAPS) including familial cold autoinflammatory syndrome (familial cold urticaria) and unspecified cardiovascular disorders. It is administered through oral route in the form of suspension. The drug candidate acts by targeting NACHT, LRR and PYD domains-containing protein 3 (NLRP3).

Ventyx Biosciences overview

Ventyx Biosciences is a clinical stage biopharmaceutical company focused on developing oral medicines for patients suffering with autoimmune and inflammatory disorders. The company is headquartered in San Diego, California, the US.

For a complete picture of VTX-2735’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 12 April 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.