VTR-297 is under clinical development by Vanda Pharmaceuticals and currently in Phase I for Onychomycosis (Tinea Unguium). According to GlobalData, Phase I drugs for Onychomycosis (Tinea Unguium) have an 88% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how VTR-297’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
VTR-297 overview
VTR-297 is under development for the treatment of relapsed and/or refractory haematological malignancies. It is administered through Intravenous infusion and topical route. It is a natural derivative of dienohydroxamic acid isolated from species of the bacterial genus Streptomyces. It acts by targeting histone deacetylase.
It was under development for the treatment of multiple myeloma, non-Hodgkin’s lymphoma and Hodgkin’s lymphoma.
Vanda Pharmaceuticals overview
Vanda Pharmaceuticals (Vanda) is a biopharmaceutical company that develops and commercializes novel therapies for the treatment of central nervous system disorders. The company’s products include Hetlioz, a melatonin receptor agonist for the treatment of non-24-hour sleep-wake disorder; Ponvory for the treatment of relapsing forms of multiple sclerosis; and Fanapt, a typical antipsychotic for the treatment of schizophrenia in adults. The company’s major pipeline products include Tradipitant (VLY-686), VTR-297, VQW-765, CFTR and a portfolio of cystic fibrosis transmembrane conductance regulator inhibitors and activators. Vanda is headquartered in Washington, Washington DC, the US.
For a complete picture of VTR-297’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
