VTP-500 is under clinical development by Barinthus Biotherapeutics and currently in Phase I for Middle East Respiratory Syndrome (MERS). According to GlobalData, Phase I drugs for Middle East Respiratory Syndrome (MERS) does not have sufficient historical data to build an indication benchmark PTSR for Phase I. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the VTP-500 LoA Report. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
VTP-500 overview
VTP-500 is under development for the prevention of Middle East respiratory syndrome (MERS) infections. It is administered through intramuscular route. The drug candidate utilizes recombinant vector ChAdOx1 to deliver the MERS coronavirus spike protein. It is developed based on Chimpanzee adenovirus technology.
Barinthus Biotherapeutics overview
Barinthus Biotherapeutics (Barinthus), formerly Vaccitech plc, is a clinical-stage biopharmaceutical company that develops novel T-cell immunotherapeutic candidates. The company’s pipeline products include VTP-300: Hepatitis B, VTP-200: Human Papillomavirus, VTP-800/850: Prostate Cancer Therapeutic, VTP-600: Cancer, VTP-1000: Celiac Disease, VTP-1100: HPV Cancer, VTP-900: Covid-19, VTP-500: MERS Prophylactic, VTP-400: Zoster Prophylactic. Its proprietary platforms, ChAdOx, MVA, and SNAPvax, are designed to harness the power of the immune system’s T cells and can be combined in prime-boost regimens, providing advantages in terms of tolerability, manufacturability and efficacy. Barinthus is headquartered in Didcot, England, the UK.
For a complete picture of VTP-500’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
