The Tyrosine Protein Kinase ITK/TSK pipeline drugs market research report outlays comprehensive information on the Tyrosine Protein Kinase ITK/TSK targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Tyrosine Protein Kinase ITK/TSK pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Immunology, Dermatology, Oncology, and Gastrointestinal which include the indications Psoriasis, Rheumatoid Arthritis, Atopic Dermatitis (Atopic Eczema), Alopecia Areata, Solid Tumor, Unspecified B-Cell Lymphomas, Ulcerative Colitis, and Inflammatory Bowel Disease. It also reviews key players involved in Tyrosine Protein Kinase ITK/TSK targeted therapeutics development with respective active and dormant or discontinued products.
The Tyrosine Protein Kinase ITK/TSK pipeline targets constitutes close to 14 molecules. Out of which, approximately 14 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 3, 1, 2, 7, and 1 respectively.
Tyrosine Protein Kinase ITK/TSK overview
Tyrosine-protein kinase ITK/TSK or interleukin-2-inducible T-cell kinase or simply ITK is a protein encoded by the ITK gene. It plays an essential role in regulation of the adaptive immune response. When antigen presenting cells (APC) activate T-cell receptor (TCR) a series of phosphorylation lead to the recruitment of ITK to the cell membrane, stimulate TCR receptor, where it is phosphorylated by LCK. Phosphorylation leads to ITK autophosphorylation and full activation. It regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells.
For a complete picture of Tyrosine Protein Kinase ITK/TSK’s drug pipeline, buy the report here.
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