Twist Bioscience has been granted a patent for a system that synthesizes and amplifies polynucleotides for biomolecule-based data storage. The system includes a synthesizer, reactor, receiving unit, and power unit, enabling efficient long-term information retention and retrieval with high accuracy. GlobalData’s report on Twist Bioscience gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Twist Bioscience, Water gas shift catalysts was a key innovation area identified from patents. Twist Bioscience's grant share as of July 2024 was 18%. Grant share is based on the ratio of number of grants to total number of patents.
Biomolecule-based data storage and synthesis system
The granted patent US12056264B2 describes a sophisticated system designed for the synthesis, amplification, and management of polynucleotides. Central to this system is a synthesizer that utilizes a wafer with multiple substrates, equipped with fluidic openings for synthesizing various polynucleotides. The system includes a reactor that amplifies these polynucleotides and facilitates their transfer through a series of channels. A receiving unit is incorporated to hold the synthesized polynucleotides, while a power unit directs their movement. Additional components such as a sequencing device and a computer system enhance the functionality of the system, allowing for data storage, retrieval, and automation of processes.
The computer system plays a crucial role, featuring a database for managing polynucleotide data and an encryption scheme for converting binary codes into nucleic acid sequences. It is also equipped with software for translating polynucleotide sequences into binary code and automating system functions, including the synchronization of material deposition and reagent dispensing. The reactor is designed with temperature control and can facilitate the transfer of reagents. Notably, the polynucleotides can encode digital sequences, potentially including barcodes for identification. The system's versatility is further highlighted by its ability to utilize various transfer media and accommodate multiple compartments within the receiving unit for organized storage of polynucleotides.
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