The Toll Like Receptor 5 pipeline drugs market research report outlays comprehensive information on the Toll Like Receptor 5 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Toll Like Receptor 5 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Oncology, Toxicology, Immunology, and Dermatology which include the indications Unspecified Cancer, Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome), Rheumatoid Arthritis, Graft Versus Host Disease (GVHD), and Alopecia. It also reviews key players involved in Toll Like Receptor 5 targeted therapeutics development with respective active and dormant or discontinued products.
The Toll Like Receptor 5 pipeline targets constitutes close to nine molecules. Out of which, approximately nine molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase I, Preclinical, and Discovery stages are 3, 4, and 2 respectively.
Toll Like Receptor 5 overview
Toll-like receptor 5 (TLR5) is a pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response. It recognizes small molecular motifs named pathogen-associated molecular pattern (PAMPs) expressed by pathogens and microbe-associated molecular patterns (MAMPs) usually expressed by resident microbiota. Upon ligand binding such as bacterial flagellins, it recruits intracellular adapter proteins MYD88 and TRIF leading to NF-kappa-B activation, cytokine secretion, and induction of the inflammatory response.
For a complete picture of Toll Like Receptor 5’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
