TNX-1500 is under clinical development by Tonix Pharmaceuticals Holding and currently in Phase I for Heart Transplant Rejection. According to GlobalData, Phase I drugs for Heart Transplant Rejection have a 75% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how TNX-1500’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
TNX-1500 overview
TNX-1500 is under development for the prevention and treatment of organ transplant rejection, prevention of graft-versus-host disease (GvHD) after hematopoietic stem cell transplantation (HCT) and for treatment of autoimmune disorders including systemic lupus erythematosus, sjogren’s syndrome, rheumatoid arthritis, multiple sclerosis and allergy. It acts by targeting CD40 ligand (CD154). It is a new molecular entity (NME). The drug candidate is administered through intravenous route.
Tonix Pharmaceuticals Holding overview
Tonix Pharmaceuticals Holding (Tonix) a developer of pharmaceutical products to address public health challenges. The company’s pipeline products include TNX-102 SL treats fibromyalgia, long covid, acute stress disorder; TNX-1300 targets cocaine intoxication; TNX-1500 is for the treatment of cocaine intoxication; TNX-1500 treats organ transplant rejection and autoimmune disorders; TNX-1700 for gastric and colorectal cancer; TNX-801 targets smallpox and monkeypox preventing vaccine; TNX-1850 treats Covid 19 vaccine; TNX-2900 is for the treatment of prader willi syndrome. It has operations in Ireland, Canada and the US. Tonix is headquartered in New York, the US
For a complete picture of TNX-1500’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
