Temuterkib is under clinical development by Eli Lilly and Co and currently in Phase I for Refractory Acute Myeloid Leukemia. According to GlobalData, Phase I drugs for Refractory Acute Myeloid Leukemia have a 68% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how Temuterkib’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Temuterkib overview
LY-3214996 is under development for the treatment of metastatic pancreatic cancer, relapsed and refractory acute myeloid leukemia, multiple tumors including metastatic non-small cell lung cancer, metastatic colorectal cancer, metastatic pancreatic ductal adenocarcinoma, metastatic melanoma and recurrent glioblastoma multiforme. It is administered orally. The drug candidate targets the extracellular-signal-regulated kinases 1 and 2 (ERK1/2). The drug candidate is a new chemical entity (NCE). It was also under development for the treatment of chronic lymphocytic leukemia, waldenstrom macroglobulinemia, mantle cell lymphoma and marginal zone lymphoma.
Eli Lilly and Co overview
Eli Lilly and Co (Lilly) is a healthcare company that discovers, develops, and markets human healthcare products. The company offers medicines for cardiovascular conditions, diabetes, endocrinology, cancer, neurological problems, autoimmune disorders, men’s health, and musculoskeletal problems. The company distributes its pharmaceutical health products through independent wholesale distributors. Lilly conducts research and development activities to discover and deliver innovative medicines. It promotes products through sales representatives and marketing agreements with other pharmaceutical companies. The company operates R&D facilities, and production and distribution facilities in North America, South America, Europe, the Middle East, Africa and Asia-Pacific. Lilly is headquartered in Indianapolis, Indiana, the US.
For a complete picture of Temuterkib’s drug-specific PTSR and LoA scores, buy the report here.
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