TAC-101 is under clinical development by Triumvira Immunologics and currently in Phase II for Pancreatic Ductal Adenocarcinoma. According to GlobalData, Phase II drugs for Pancreatic Ductal Adenocarcinoma does not have sufficient historical data to build an indication benchmark PTSR for Phase II. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the TAC-101 LoA Report. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
TAC-101 overview
TAC-101 is under development for the treatment of solid tumor include gastric, GEJ, esophageal adenocarcinoma, PDAC, colorectal cancer, cholangiocarcinoma, ovarian mucinous cancer, gallbladder cancer and NSCLC.. The therapeutic candidate comprises autologous T-cells which are engineered to express T cell Antigen Coupler (TAC) complex targeting claudin 18.2 expressing tumor cells. It is being developed based on T-cell antigen coupler (TAC) technology. It is administered through intravenous route.
Triumvira Immunologics overview
Triumvira Immunologics (Triumvira) is a biopharmaceutical company that develops novel cancer therapies. The company involved in the investigation of the mechanism in which TAC directs the engineered T-cells to target antigens and activates the T-cells after binding with antigen. The company’s product pipeline includes TAC101-Claudin18.2 and TAC201-Claudin18.2 for gastro pancreatic ductal adenocarcinoma and TACX03-GUCY2C and TACX04-GPC3 for the treatment of colon rectal, gastroesophageal junction adenocarcinoma, and hepatocellular carcinoma. It operates a research facility in Hamilton, Ontario, Canada. Triumvira is headquartered in Austin, Texas, the US.
For a complete picture of TAC-101’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
