Suvecaltamide Hydrochloride is a small molecule commercialized by Jazz Pharmaceuticals, with a leading Phase II program in Essential Tremor. According to Globaldata, it is involved in 6 clinical trials, of which 5 were completed, and 1 is ongoing. GlobalData uses proprietary data and analytics to provide a complete picture of Suvecaltamide Hydrochloride’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
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The revenue for Suvecaltamide Hydrochloride is expected to reach an annual total of $275 mn by 2035 globally based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
Suvecaltamide Hydrochloride Overview
JZP-385 (CX-8998) is under development for the treatment of neurological diseases essential tremor, tremor associated with Parkinson's disease. It acts by targeting T Type Calcium Channel (CaV3). The drug candidate is administered through oral route.
It was also development for the treatment of schizophrenia, including absence seizures, childhood absence epilepsy, juvenile absence epilepsy, juvenile myoclonic epilepsy, jeavons syndrome, and insomnia.
Jazz Pharmaceuticals Overview
Jazz Pharmaceuticals is a specialty biopharmaceutical company which identifies, develops and commercializes medicines with focus on narcolepsy, cancer, pain, and psychiatry. Its marketed products include Xyrem (sodium oxybate) oral solution, Sunosi (solriamfetol), Erwinaze (asparaginase erwinia chrysanthemi), Defitelio (defibrotide sodium), Vyxeos (daunorubicin and cytarabine) liposome for injection, and others. The company also has various pipeline product candidates related to focus areas such as sleep, neurological disorders, hematology, and oncology including hematologic malignancies and solid tumors. The company sells its products through a network of local distributors and wholesalers. It has operations in the US and Europe. Jazz Pharmaceuticals is headquartered in Dublin, Ireland.
The company reported revenues of (US Dollars) US$3,834.2 million for the fiscal year ended December 2023 (FY2023), an increase of 4.8% over FY2022. The operating profit of the company was US$578.6 million in FY2023, compared to an operating loss of US$65.5 million in FY2022. The net profit of the company was US$414.8 million in FY2023, compared to a net loss of US$224.1 million in FY2022.
The company reported revenues of US$1,023.8 million for the second quarter ended June 2024, an increase of 13.5% over the previous quarter.
For a complete picture of Suvecaltamide Hydrochloride’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company.
The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s Pharmaceutical Intelligence Center.
