SNS-101 is a monoclonal antibody commercialized by Sensei Biotherapeutics, with a leading Phase II program in Head And Neck Cancer;Non-Small Cell Lung Cancer. According to Globaldata, it is involved in 1 clinical trial, which is ongoing. GlobalData uses proprietary data and analytics to provide a complete picture of SNS-101’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
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The revenue for SNS-101 is expected to reach an annual total of $26 mn by 2040 globally based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
SNS-101 Overview
Sensei Biotherapeutics Overview
Sensei Biotherapeutics is an immuno-oncology company that discovers, develops and commercializes next-generation therapeutics for cancer patients. The company pipeline products include SNS-101, SNS-201SNS-102 and SNS-103 for the treatment of solid tumors. The company through its TMAb (Tumor Microenvironment Activated Biologics) platform, develops highly selective therapeutics designed to disable immunosuppressive signals or activate immunostimulatory signals selectively in the tumor microenvironment. Sensei Biotherapeutics collaborates with Regeneron Pharmaceuticals and the National Cancer Institute (NCI) for the development of drugs. Sensei is headquartered in Rockville, Maryland, the US.
The operating loss of the company was US$37.1 million in FY2023, compared to an operating loss of US$50.2 million in FY2022. The net loss of the company was US$34.1 million in FY2023, compared to a net loss of US$48.6 million in FY2022.
For a complete picture of SNS-101’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company.
The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s Pharmaceutical Intelligence Center.
