Shanghai Junshi Bioscience has been granted a patent for isotope-enriched compounds with heavy isotope-enriched amide functional groups. These compounds can modulate drug properties and enhance therapeutic effects. The patent also covers the use of these compounds for treating various diseases. GlobalData’s report on Shanghai Junshi Bioscience gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Shanghai Junshi Bioscience, Personalized cancer vaccines was a key innovation area identified from patents. Shanghai Junshi Bioscience's grant share as of May 2024 was 18%. Grant share is based on the ratio of number of grants to total number of patents.
Isotope-enriched compounds for drug delivery modulation
A recently granted patent (Publication Number: US11970490B2) discloses an isotope-enriched compound containing a heavy isotope-enriched amide functional group. The compound is characterized by a high level of isotope-enrichment, ranging from 90% to 100%, as determined by mass spectrometry. This compound is utilized in a pharmaceutical composition suitable for oral administration, aimed at treating PI3K mediated diseases such as melanoma, colorectal adenoma, breast cancer, or pancreatic cancer.
Moreover, the patent outlines methods of treatment involving the administration of the isotope-enriched compound either in free form or as part of a pharmaceutical composition. The treatment regimen may also include the use of fulvestrant in conjunction with the compound. Dosage ranges from 50 mg to 500 mg, with a specific recommendation of 300 mg administered once daily. The compound's high level of isotope-enrichment, at 94% or higher, ensures its efficacy in targeting PI3K mediated diseases, particularly breast cancer subtypes like hormone receptor positive (HR+) and human epidermal growth factor receptor negative (HER2-). The patent underscores the potential of this isotope-enriched compound in advancing treatment strategies for various diseases.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
