Selicrelumab is under clinical development by F. Hoffmann-La Roche and currently in Phase II for Head And Neck Squamous Cell Carcinoma (HNSC). According to GlobalData, Phase II drugs for Head And Neck Squamous Cell Carcinoma (HNSC) have a 26% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Selicrelumab’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Selicrelumab overview
Selicrelumab is under development for the treatment of recurrent or refractory B-non-Hodgkin's lymphoma, metastatic pancreatic ductal adenocarcinoma, head and neck squamous cell carcinoma, triple negative breast cancer, metastatic ovarian cancer, gastric cancer, metastatic colorectal cancer, metastatic pancreatic cancer, metastatic melanoma, malignant mesothelioma, non-squamous non-small cell lung cancer, drug resistant advanced and/or metastatic solid tumors such as platinum-resistant ovarian carcinoma and newly diagnosed pancreatic adenocarcinoma. It is a new molecular entity (NME). It is administered intravenously, intratumoral and subcutaneously. The drug candidate targets B Cell Surface Antigen CD40.
F. Hoffmann-La Roche overview
F. Hoffmann-La Roche (Roche) is a biotechnology company and a provider of in-vitro diagnostics as well as a supplier of transformative innovative solutions across major disease areas. It provides drugs for the treatment of cancer, other auto-immune diseases, central nervous system disorders, ophthalmological disorders, infectious diseases, and respiratory diseases. The company also offers in vitro diagnostics, tissue-based cancer diagnostics, and diabetes management solutions. Roche conducts research to identify novel methods to prevent, diagnose, and treat diseases. The company offers its products and services to hospitals, healthcare professionals, commercial laboratories, researchers and pharmacists. Roche is headquartered in Basel, Switzerland.
For a complete picture of Selicrelumab’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
