Rogaratinib is under clinical development by Bayer and currently in Phase I for Solid Tumor. According to GlobalData, Phase I drugs for Solid Tumor have a 69% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how Rogaratinib’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Rogaratinib overview
Rogaratinib (BAY-1163877) is under development for the treatment of non-muscle invasive bladder cancer, refractory, locally advanced or metastatic solid tumors including squamous non-small cell lung cancer, metastatic urothelial carcinoma including urinary bladder, renal pelvis, ureters, urethra carcinomas, lung adenocarcinoma, squamous cell carcinoma of the head and neck, hepatocellular carcinoma, adenoid cystic carcinoma, gastrointestinal stromal tumor and sarcoma. The drug candidate is administered orally. It acts by targeting fibroblast growth factor receptors (FGFR).
It was also under development for the treatment of breast cancer.
Bayer overview
Bayer carries out the discovery, development, manufacturing, and commercialization of products for human health, and agriculture. It provides medicines for cardiovascular diseases, women’s health, cancer, hematology, ophthalmology, and other indications. It also strives to develop new molecules and technologies for use in the fields of medicine and modern agriculture. The company’s product portfolio includes prescription products, specialty pharmaceuticals, diagnostic imaging equipment, non-prescription (over-the-counter or OTC) products, seeds, crop protection solutions and non-agricultural pest control solutions. Bayer markets its products through wholesalers, pharmacies, hospitals, and retailers. It operates through a network of subsidiaries in Asia-Pacific, Europe, North America, Latin America, Africa, and the Middle East. Bayer is headquartered in Leverkusen, North Rhine-Westphalia, Germany.
For a complete picture of Rogaratinib’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
