Rigel Pharmaceuticals. has been granted a patent for kinase inhibitory compounds, specifically targeting receptor-interacting protein-1 (RIP1) kinase. These compounds may be used in pharmaceutical compositions to treat or prevent various diseases associated with RIP1, including amyotrophic lateral sclerosis, type I diabetes, and rheumatoid arthritis. GlobalData’s report on Rigel Pharmaceuticals gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Rigel Pharmaceuticals, Cancer treatment biomarkers was a key innovation area identified from patents. Rigel Pharmaceuticals's grant share as of July 2024 was 52%. Grant share is based on the ratio of number of grants to total number of patents.
The granted patent US12043629B2 outlines methods for treating various diseases associated with receptor-interacting protein-1 (RIP1) kinase. The claims specify that a therapeutically effective amount of a compound, referred to as Formula I, can be administered to subjects diagnosed with or suspected of having diseases such as amyotrophic lateral sclerosis (ALS), type I diabetes, rheumatoid arthritis, Crohn's disease, ulcerative colitis, multiple sclerosis, asthma, or leukemia. The patent also encompasses pharmaceutical compositions that include Formula I along with one or more pharmaceutically acceptable excipients, emphasizing the versatility of the treatment approach across multiple conditions linked to RIP1 kinase.
Additionally, the patent includes claims focused on the inhibition of RIP1 kinase in subjects, reiterating the therapeutic potential of the compounds described. The methods outlined in the claims are applicable to a range of diseases, with specific emphasis on ALS and multiple sclerosis in certain claims. This highlights the potential for targeted therapies that could address the underlying mechanisms of these diseases through the modulation of RIP1 kinase activity, thereby offering new avenues for treatment in patients suffering from these serious health conditions.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
