The Retinoid Isomerohydrolase pipeline drugs market research report outlays comprehensive information on the Retinoid Isomerohydrolase targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Retinoid Isomerohydrolase pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Ophthalmology which include the indications Leber Congenital Amaurosis (LCA), and Choroideremia. It also reviews key players involved in Retinoid Isomerohydrolase targeted therapeutics development with respective active and dormant or discontinued products.
The Retinoid Isomerohydrolase pipeline targets constitutes close to seven molecules. Out of which, approximately six molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, and Phase I stages are 1, 4, and 1 respectively. Similarly, the universities portfolio in Preclinical comprises 1 molecule.
Retinoid Isomerohydrolase overview
Retinoid Isomerohydrolase is an enzyme crucial for the regeneration of 11-cis-retinal, which serves as the chromophore for rod and cone opsins in the visual system. Its main role involves catalyzing the cleavage and isomerization of all-trans-retinyl fatty acid esters, converting them into 11-cis-retinol. This 11-cis-retinol is subsequently oxidized by 11-cis retinol dehydrogenase to form 11-cis-retinal, which is essential for visual processes. Additionally, Retinoid Isomerohydrolase has the capability to facilitate the isomerization of lutein to meso-zeaxanthin, a carotenoid specific to the eye.
For a complete picture of Retinoid Isomerohydrolase’s drug pipeline, buy the report here.
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