The Receptor Tyrosine Protein Kinase ERBB 2 pipeline drugs market research report outlays comprehensive information on the Receptor Tyrosine Protein Kinase ERBB 2 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Receptor Tyrosine Protein Kinase ERBB 2 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Oncology, Undisclosed, Respiratory, and Women’s Health which include the indications Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (HER2+ Breast Cancer), Solid Tumor, Unspecified, Unspecified Rare Disease, Unspecified Respiratory Disorders, and Ovarian Disease. It also reviews key players involved in Receptor Tyrosine Protein Kinase ERBB 2 targeted therapeutics development with respective active and dormant or discontinued products.
The Receptor Tyrosine Protein Kinase ERBB 2 pipeline targets constitutes close to 369 molecules. Out of which, approximately 332 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Filing rejected/ Withdrawn, Phase III, Phase II, Phase I, Phase 0, IND/ CTA Filed, Preclinical, and Discovery stages are 10, 4, 33, 37, 57, 2, 11, 141, and 36 respectively. Similarly, the universities portfolio in Phase II, Phase I, Phase 0, Preclinical, and Discovery comprises 6, 5, 3, 17, and 6 molecule.
Receptor Tyrosine Protein Kinase ERBB 2 overview
Receptor tyrosine-protein kinase ERBB 2 is a protein that is found on the surface of cells. It is a member of the epidermal growth factor receptor (EGFR) family. Activation of HER2 mediated signaling pathways occurs by heterodimerization with ligand-activated EGFR or HER3 or by homodimerization. These dimerizations would lead to phosphorylation of tyrosine residues, which initiates downstream signaling cascades such as PI3K/AKT signaling cascade, Ras/MEK/ERK, and JAK/STAT, that regulate cell survival, proliferation, differentiation, motility, apoptosis, survival, invasion, migration, adhesion, and angiogenesis.
For a complete picture of Receptor Tyrosine Protein Kinase ERBB 2’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
