The Pyruvate Kinase PKM pipeline drugs market research report outlays comprehensive information on the Pyruvate Kinase PKM targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Pyruvate Kinase PKM pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Oncology, Respiratory, Immunology, and Gastrointestinal which include the indications Oncology, Lung Cancer, Idiopathic Pulmonary Fibrosis, Interstitial Lung Fibrosis, Psoriasis, Rheumatoid Arthritis, Inflammatory Bowel Disease, and Metabolic Dysfunction-Associated Steatohepatitis (MASH). It also reviews key players involved in Pyruvate Kinase PKM targeted therapeutics development with respective active and dormant or discontinued products.
The Pyruvate Kinase PKM pipeline targets constitutes close to seven molecules. Out of which, approximately six molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Preclinical, and Discovery stages are 1, 2, and 3 respectively. Similarly, the universities portfolio in Discovery comprises 1 molecule.
Pyruvate Kinase PKM overview
Pyruvate Kinase PKM (PKM) catalyzes the final rate-limiting step of glycolysis by mediating the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. It interacts with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. PKM binds to Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
For a complete picture of Pyruvate Kinase PKM’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
