The Plasminogen pipeline drugs market research report outlays comprehensive information on the Plasminogen targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Plasminogen pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Cardiovascular, Hematological Disorders, Dermatology, and Genetic Disorders which include the indications Acute Ischemic Stroke, Myocardial Infarction, Bleeding And Clotting Disorders, Hemophilia A (Factor VIII Deficiency), Diabetic Foot Ulcers, and Congenital Plasminogen Deficiency. It also reviews key players involved in Plasminogen targeted therapeutics development with respective active and dormant or discontinued products.
The Plasminogen pipeline targets constitutes close to 22 molecules. Out of which, approximately 21 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 4, 3, 2, 1, 5, and 4 respectively. Similarly, the universities portfolio in Preclinical comprises 1 molecule.
Plasminogen overview
Plasminogen dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, it weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases, and several complement zymogens such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis.
For a complete picture of Plasminogen’s drug pipeline, buy the report here.
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