OptiBiotix Health has been granted a patent for a modified non-digestible prebiotic oligosaccharide that incorporates monosaccharide units, enhancing its sweetness compared to unmodified versions. The patent details methods for producing these oligosaccharides and their potential applications. GlobalData’s report on OptiBiotix Health gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on OptiBiotix Health, Low glycaemic index foods was a key innovation area identified from patents. OptiBiotix Health's grant share as of June 2024 was 29%. Grant share is based on the ratio of number of grants to total number of patents.

Modified prebiotic oligosaccharides with increased sweetness value

Source: United States Patent and Trademark Office (USPTO). Credit: OptiBiotix Health Plc

The granted patent US12042506B2 outlines a prebiotic formulation that includes one or more non-digestible oligosaccharides, specifically highlighting the modification of these oligosaccharides to enhance their sweetness. At least one of the oligosaccharides is modified to incorporate monosaccharides, resulting in a higher sweetness value compared to its unmodified counterpart. The formulation includes fructose-modified galactooligosaccharides (GOS) and may also contain other non-digestible oligosaccharides such as inulin, fructooligosaccharides (FOS), a-galactooligosaccharides, and ß-glucooligosaccharides. The modified oligosaccharides can constitute up to 95% of the total composition, with the remainder being unmodified oligosaccharides.

The patent further details the methods for synthesizing these modified oligosaccharides, which involve reactions between disaccharide or oligosaccharide precursors and monosaccharide acceptors. Specific enzymes, such as galactosidase or glycosidase, are employed during the synthesis process to facilitate the modification. Notably, the patent mentions the use of ß-galactosidase derived from the Aspergillus genus for fructosylation, with fructose as a potential monosaccharide acceptor. The prebiotic formulation can be presented in granular or powdered form and is intended for incorporation into food products, supplements, or as a sweetener, thereby enhancing the sweetness profile while providing prebiotic benefits.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies