Omeros has been granted a patent for a method to prevent angiogenesis in mammals with angiogenesis-dependent diseases. The method involves administering a MASP-2 inhibitory agent, such as a MASP-2 antibody, to inhibit the process. Claim 1 specifically focuses on treating benign tumors using a MASP-2 inhibitory monoclonal antibody. GlobalData’s report on Omeros gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on Omeros, Peptide pharmacophores was a key innovation area identified from patents. Omeros's grant share as of May 2024 was 44%. Grant share is based on the ratio of number of grants to total number of patents.
Treating benign tumors by inhibiting angiogenesis with masp-2 antibody
A recently granted patent (Publication Number: US11981748B2) discloses a method for treating angiogenesis-dependent benign tumors in mammalian subjects. The method involves administering a MASP-2 inhibitory agent, specifically a MASP-2 inhibitory monoclonal antibody or its fragment, to inhibit angiogenesis. The monoclonal antibody or fragment includes specific heavy and light chain variable regions as defined by SEQ ID NO:67 and SEQ ID NO:69.
Furthermore, the patent claims cover the administration of the composition through various routes such as subcutaneous, intraperitoneal, intramuscular, intra-arterial, intravenous, or as an inhalant. This method aims to effectively inhibit angiogenesis in benign tumors like hemangiomas, acoustic neuromas, neurofibromas, trachomas, carcinoid tumors, and pyogenic granulomas in mammalian subjects. The specificity of the MASP-2 inhibitory agent and the defined administration routes highlight the innovative approach proposed in this patent for treating angiogenesis-dependent benign tumors.
To know more about GlobalData’s detailed insights on Omeros, buy the report here.
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