MWTx-01 is under clinical development by Disc Medicine and currently in Phase I for Polycythemia Vera. According to GlobalData, Phase I drugs for Polycythemia Vera have an 82% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how MWTx-01’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
MWTx-01 overview
MWTx-01 is under development for the treatment of beta-thalassemia and sickle cell disease, Polycythemia Vera. The therapeutic candidate is a humanized monoclonal antibody that is administered through intravenous or subcutaneous route. It acts by targeting transmembrane protease serine 6 (TMPRSS6).
Disc Medicine overview
Disc Medicine is a clinical-stage biopharmaceutical company primarily that focuses on advancing the field of hematology through the development of innovative therapies. The company’s main activities involve the research and development of treatments for hematologic diseases, with a particular emphasis on red blood cell biology. Its pipeline products include bitopertin for the treatment of erythropoietic porphyria’s, including erythropoietic protoporphyria, X-linked protoporphyria and Diamond-Blackfan Anemia:, DISC-0974 for the treatment of anemia of myelofibrosis and and anemia of chronic kidney disease. Disc Medicine is headquartered in Cambridge, Massachusetts, the US.
For a complete picture of MWTx-01’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
