The Mucin 1 pipeline drugs market research report outlays comprehensive information on the Mucin 1 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Mucin 1 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Non Malignant Disorders, Undisclosed, and Infectious Disease which include the indications Solid Tumor, Non-Small Cell Lung Cancer, Adenomas, Unspecified, and Coronavirus Disease 2019 (COVID-19). It also reviews key players involved in Mucin 1 targeted therapeutics development with respective active and dormant or discontinued products.
The Mucin 1 pipeline targets constitutes close to 70 molecules. Out of which, approximately 55 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 9, 6, 1, 27, and 12 respectively. Similarly, the universities portfolio in Phase II, Phase I, Phase 0, Preclinical, and Discovery comprises 5, 3, 2, 3, and 2 molecule.
Mucin 1 overview
Mucin 1, cell surface associated (MUC1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene. It acts both as an adhesion and an anti-adhesion protein. It provides a protective layer on epithelial cells against bacterial and enzyme attack. It is involved in cell signaling through phosphorylations and protein-protein interactions. It modulates signaling in ERK, SRC and NF-kappa-B pathways. It promotes tumor progression. It regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response.
For a complete picture of Mucin 1’s drug pipeline, buy the report here.
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