Mochida Pharmaceutical has filed a patent for a sheet-like material that prevents adhesion. The material contains alginate, which is crosslinked with a curing agent. The material undergoes a dissolution test, where a sample is placed on agar in a petri dish and shaken. The weight of the sample is measured at different time points. The material meets two criteria: the weight of the sample becomes less than 0.01 g within 5-36 hours, and the weight reaches its maximum within 10 hours or less. GlobalData’s report on Mochida Pharmaceutical gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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A sheet-like material for preventing adhesion
A recently filed patent (Publication Number: US20230293782A1) describes a sheet-like material for preventing adhesion. The material contains alginate, a substance derived from seaweed, which is crosslinked with a curing agent. The patent claims that the material meets specific criteria when tested for dissolution. In the dissolution test, a sample of the material is placed on agar in a petri dish and shaken, and the weight of the sample is measured at various time points. The patent claims that the material meets two specific requirements: (1) the time required for the weight of the sample to be less than 0.01 g is between 5 and 36 hours from the start of the test, and (2) the time required for the weight of the sample to reach its maximum weight is 10 hours or less from the start of the test.
The patent also describes the material as having a first layer and a second layer, with the dissolution rate of the first layer being slower than that of the second layer. The total amount of alginate in the material is specified to be between 1.4 mg/cm² and 2.8 mg/cm², and the curing agent is a calcium ion compound with a total amount of calcium between 0.14 mg/cm² and 0.30 mg/cm². The thickness of the sheet-like material is stated to be between 100 µm and 500 µm. The patent also mentions that the material can be a single layer or can have additional layers formed through a specific production method.
Furthermore, the patent describes a method for producing the material, which involves curing an aqueous solution of a monovalent metal salt of alginic acid with a curing agent, optionally freezing the cured material, and optionally repeating the curing and freezing steps to form multiple layers. The method also includes a step of lyophilizing the resulting cured material.
Additionally, the patent claims a method for preventing adhesion by applying the sheet-like material to a subject in need of adhesion prevention. The material is described as containing alginate crosslinked with a curing agent and meeting the dissolution test criteria mentioned earlier.
In conclusion, the filed patent describes a sheet-like material for preventing adhesion that contains alginate crosslinked with a curing agent. The material meets specific dissolution test criteria and can have multiple layers. The patent also includes a method for producing the material and a method for preventing adhesion using the material.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
