The Mitogen Activated Protein Kinase Kinase Kinase 5 pipeline drugs market research report outlays comprehensive information on the Mitogen Activated Protein Kinase Kinase Kinase 5 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Mitogen Activated Protein Kinase Kinase Kinase 5 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Cardiovascular, Central Nervous System, Gastrointestinal, and Genito Urinary System which include the indications Myocardial Infarction, Pulmonary Hypertension, Parkinson’s Disease, Amyotrophic Lateral Sclerosis, Metabolic Dysfunction-Associated Steatohepatitis (MASH), Liver Fibrosis, Acute Renal Failure (ARF) (Acute Kidney Injury), and Chronic Kidney Disease (Chronic Renal Failure). It also reviews key players involved in Mitogen Activated Protein Kinase Kinase Kinase 5 targeted therapeutics development with respective active and dormant or discontinued products.
The Mitogen Activated Protein Kinase Kinase Kinase 5 pipeline targets constitutes close to 13 molecules. Out of which, approximately ten molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase I, Preclinical, and Discovery stages are 2, 6, and 2 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 1, and 2 molecule.
Mitogen Activated Protein Kinase Kinase Kinase 5 overview
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5) is a member of MAP kinase kinase kinase family encoded by MAP3K5 gene. It plays an important role in the cascades of cellular responses evoked by changes in the environment. It mediates signaling for determination of cell fate such as differentiation and survival. It plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation. It is essential for host defense against a wide range of pathogens. It mediates signal transduction of various stressors like oxidative stress as well as by receptor-mediated inflammatory signals.
For a complete picture of Mitogen Activated Protein Kinase Kinase Kinase 5’s drug pipeline, buy the report here.
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