Mind Medicine MindMed. has been granted a patent for a solid oral immediate release formulation of LSD, created through lyophilization in a pre-formed mold to produce an orally disintegrating tablet. The formulation includes specific excipients such as maltodextrin, hydroxypropyl methylcellulose, and mannitol or trehalose. GlobalData’s report on Mind Medicine MindMed gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Mind Medicine MindMed, Nanoparticle drug conjugates was a key innovation area identified from patents. Mind Medicine MindMed's grant share as of July 2024 was 9%. Grant share is based on the ratio of number of grants to total number of patents.
Lsd orally disintegrating tablet formulation and manufacturing method
The granted patent US12036220B2 outlines a novel formulation and method for producing an orally disintegrating LSD tablet. The tablet is created through lyophilization of a stock solution that includes a non-gelling matrix former (maltodextrin), a binder (hydroxypropyl methylcellulose), and a filler (either mannitol or trehalose), along with LSD tartrate at less than 1% weight and water. The process involves flash freezing the stock solution in a pre-formed mold, followed by lyophilization, resulting in a tablet that can disintegrate in less than 60 seconds. The patent also allows for the inclusion of a buffer, such as citrate, phosphate, or acetate, to enhance the formulation.
Additionally, the patent describes methods for administering the LSD tablet to individuals who may have difficulty swallowing, such as the elderly or those with dementia. The therapeutic applications of the LSD tablet include treatment for various conditions, including anxiety disorders, depression, and neurodegenerative disorders, among others. The administration dosage is specified to be between 0.01 to 1 mg of LSD. This patent represents a significant advancement in the formulation and delivery of LSD for therapeutic use, particularly for populations that may benefit from rapid disintegration and ease of administration.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
