The Methionine Aminopeptidase 2 pipeline drugs market research report outlays comprehensive information on the Methionine Aminopeptidase 2 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Methionine Aminopeptidase 2 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Infectious Disease, and Metabolic Disorders which include the indications Unspecified Cancer, Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer (HER2- Breast Cancer), Giardiasis, Amoebic Infections, and Obesity. It also reviews key players involved in Methionine Aminopeptidase 2 targeted therapeutics development with respective active and dormant or discontinued products.
The Methionine Aminopeptidase 2 pipeline targets constitutes close to six molecules. Out of which, approximately four molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, and Preclinical stages are 1, 1, and 1 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 1, and 1 molecule.
Methionine Aminopeptidase 2 overview
Methionine aminopeptidase 2 is an enzyme that in humans is encoded by the METAP2 gene. Methionine aminopeptidase 2 is a member of the dimetallohydrolase family is a cytosolic metalloenzyme that catalyzes the hydrolytic removal of N-terminal methionine residues from nascent proteins. Increased expression of this METAP2 is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of METAP2 have shown to be effective for the treatment of obesity.
For a complete picture of Methionine Aminopeptidase 2’s drug pipeline, buy the report here.
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