Memorial Sloan Kettering Cancer Center has been granted a patent for compounds that may treat or prevent protozoan infections, including Chagas disease, malaria, and sleeping sickness. The patent includes pharmaceutical compositions, kits, and methods related to these compounds. GlobalData’s report on Memorial Sloan Kettering Cancer Center gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Memorial Sloan Kettering Cancer Center, was a key innovation area identified from patents. Memorial Sloan Kettering Cancer Center's grant share as of July 2024 was 37%. Grant share is based on the ratio of number of grants to total number of patents.

Compounds for treating protozoan infections and related diseases

Source: United States Patent and Trademark Office (USPTO). Credit: Memorial Sloan Kettering Cancer Center

The granted patent US12071436B2 encompasses a series of claims related to specific chemical compounds, particularly those represented by Formula (I') and its derivatives. The claims detail various structural configurations of these compounds, including specific variations denoted as Formula (I'-A), (I'-B), and (I'-C). Additionally, the claims specify conditions regarding substituents, such as R1, R2, R3, and R4, which can take on various chemical forms, including hydrogen and alkyl groups. The patent also covers pharmaceutically acceptable salts of these compounds, indicating their potential utility in pharmaceutical applications.

Furthermore, the patent outlines a pharmaceutical composition that includes the compounds of claim 1 along with a pharmaceutically acceptable excipient. A significant aspect of the patent is its application in treating parasitic infectious diseases, as it describes a method for administering an effective amount of the claimed compounds to subjects in need. The claims provide a comprehensive framework for the development of therapeutic agents targeting parasitic infections, highlighting the versatility and potential efficacy of the compounds described.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies