Melinta Therapeutics has been granted a patent for methods of preparing boronate derivatives for antimicrobial compounds. The patent includes a method for reducing a ketone group to form a compound of Formula (B) using a Ruthenium based catalyst system or alcohol dehydrogenase bioreduction system. GlobalData’s report on Melinta Therapeutics gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Melinta Therapeutics, NSAID cancer drugs was a key innovation area identified from patents. Melinta Therapeutics's grant share as of May 2024 was 36%. Grant share is based on the ratio of number of grants to total number of patents.
Antimicrobial compound preparation using boronate derivatives
A recently granted patent (Publication Number: US11999757B2) discloses a series of compounds and methods for their synthesis. The patent claims a compound with a specific structure (Formula I) and further specifies variations in the structure, such as the presence of a chlorine atom and the number of repeating units. Additionally, the patent describes methods for producing compounds of Formulas B, C, D, E, and F through various chemical reactions involving reduction of ketone groups and complexing agents.
The patent outlines a method for synthesizing compounds of interest by reacting specific starting materials and employing various chemical transformations. For instance, the method involves reducing the ketone group of a compound to obtain the desired structure. Furthermore, the patent details the use of specific reagents and conditions, such as reacting boronate compounds with designated compounds to yield the desired products. Overall, the patent provides a comprehensive guide for producing compounds with defined structures and properties, offering insights into the chemical processes involved in their synthesis.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
