MB-105 is under clinical development by Mustang Bio and currently in Phase I for Pancreatic Cancer. According to GlobalData, Phase I drugs for Pancreatic Cancer have a 74% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how MB-105’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

MB-105 overview

MB-105 is under development for the treatment of metastatic castration resistant prostate cancer, pancreatic cancer, gastric cancer, and bladder cancer. The therapeutic candidate comprises of autologous T lymphocytes targeting prostate stem cell antigen (PSCA) and CD19 which is done by virus to insert piece of DNA in immune cells. It is developed based on PSCA CAR T technology (PSCA technology).

Mustang Bio overview

Mustang Bio is an US based developer of cell and gene therapies for the treatment of AML and brain cancer.

For a complete picture of MB-105’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 18 March 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.