Luvixasertib is under clinical development by Treadwell Therapeutics and currently in Phase II for Leiomyosarcoma. According to GlobalData, Phase II drugs for Leiomyosarcoma have a 17% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Luvixasertib’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Luvixasertib overview
luvixasertib (CFI-402257) is under development for the treatment of advanced solid tumors, colorectal cancer; endometrial cancer; hepatocellular carcinoma; leiomyosarcoma; pancreatic Cancer; sarcomas, lung cancer and advanced or metastatic ER positive/Her2 negative breast cancer. The drug candidate is administered through oral route in the form of capsule. It belongs to pyrazolo-pyrimidines class. The drug candidate acts by targeting tyrosine threonine (TTK/MPS1) protein kinase.
It was also under development for the treatment of castrate refractory prostate cancer.
Treadwell Therapeutics overview
Treadwell Therapeutics is a clinical-stage biotechnology company that develops novel therapeutics for highly aggressive cancers. The company’s pipeline products include small cell therapeutic products, biologic therapy and T-cell receptor (TCR) based cell therapy products. Its products are used in therapeutic areas that include solid and liquid tumors, breast cancer, prostate cancer, myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML), among others. Treadwell Therapeutics leverages deep mechanistic insights and internal discovery tools to uncover novel targets and translate those insights into clinical candidates. The company operates in the US, Canada and Hong Kong. Treadwell Therapeutics is headquartered in New York City, New York, the US.
For a complete picture of Luvixasertib’s drug-specific PTSR and LoA scores, buy the report here.
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