LPMX-2 is under clinical development by LipoMedix Pharmaceutical and currently in Phase I for Bladder Cancer. According to GlobalData, Phase I drugs for Bladder Cancer have a 75% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how LPMX-2’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
LPMX-2 overview
LPMX-2 (PromiFol) is under development for the treatment of bladder cancer. It is administered through intravesical route. The drug candidate is a folate-targeted PEGylated liposomal mitomycin-C lipid-based prodrug. The drug candidate is developed based on PEGylated liposomal formulation technology.
LipoMedix Pharmaceutical overview
LipoMedix Pharmaceutical (LipoMedix) operates as a developer of drugs for cancer therapy based on liposome delivery. The company’s product Promitil is a chemotherapeutic agent, which is used for treating cancer patients with solid tumors. It conducts clinical and pharmaceutical development of a patented prodrug of mitomycin-C (MMC) and its effective delivery in liposomes to cancer affected organs. The company’s pipeline portfolio offers Promitil (LPMX-1) which has completed Phase 1a study and targeted form of Promitil (LPMX-2) is in preclinical stage. It develops products to treat various types of cancers such as breast, stomach, colon, anal and bladder cancers. LipoMedix is headquartered in Jerusalem, Israel.
For a complete picture of LPMX-2’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
