The Leukocyte Surface Antigen CD47 pipeline drugs market research report outlays comprehensive information on the Leukocyte Surface Antigen CD47 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Leukocyte Surface Antigen CD47 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Oncology, Cardiovascular, Undisclosed, and Central Nervous System which include the indications Solid Tumor, Lymphoma, Cardiovascular Disease, Atherosclerosis, Unspecified, Alzheimer’s Disease, and Amyotrophic Lateral Sclerosis. It also reviews key players involved in Leukocyte Surface Antigen CD47 targeted therapeutics development with respective active and dormant or discontinued products.
The Leukocyte Surface Antigen CD47 pipeline targets constitutes close to 115 molecules. Out of which, approximately 114 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 4, 16, 28, 4, 48, and 14 respectively. Similarly, the universities portfolio in Preclinical comprises 1 molecule.
Leukocyte Surface Antigen CD47 overview
CD47 (Cluster of Differentiation 47) or integrin associated protein (IAP) is a transmembrane protein encoded by the CD47 gene. It has a role in both cell adhesions by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). It acts as a receptor for SIRPA. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and co-stimulates T-cell activation. It plays an important role in membrane transport and/or integrin dependent signal transduction. It prevents premature elimination of red blood cells.
For a complete picture of Leukocyte Surface Antigen CD47’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
