The Leucine Rich Repeat Containing Protein 32 pipeline drugs market research report outlays comprehensive information on the Leucine Rich Repeat Containing Protein 32 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Leucine Rich Repeat Containing Protein 32 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Respiratory, and Genito Urinary System which include the indications Solid Tumor, Non-Small Cell Lung Cancer, Idiopathic Pulmonary Fibrosis, and Kidney Fibrosis. It also reviews key players involved in Leucine Rich Repeat Containing Protein 32 targeted therapeutics development with respective active and dormant or discontinued products.
The Leucine Rich Repeat Containing Protein 32 pipeline targets constitutes close to six molecules. Out of which, approximately six molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase I, and Preclinical stages are 1, 3, and 2 respectively.
Leucine Rich Repeat Containing Protein 32 overview
Leucine Rich Repeat Containing Protein 32 (LRRC32), also known as Glycoprotein A Repetitions Predominant (GARP), is a cell surface protein that plays a role in immune regulation and T-cell function. LRRC32 is primarily expressed on regulatory T cells (Tregs), a subset of T cells known for their immunosuppressive functions. LRRC32/GARP has been identified as a marker for activated Tregs, and its expression is associated with enhanced suppressive activity of these cells. The protein LRRC32 contains leucine-rich repeats, structural motifs involved in protein-protein interactions. It has been shown to interact with latent transforming growth factor-beta (TGF-beta) on the surface of Tregs. This interaction is thought to contribute to the activation of TGF-beta, a cytokine with immunosuppressive properties.
For a complete picture of Leucine Rich Repeat Containing Protein 32’s drug pipeline, buy the report here.
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