The Leptin Receptor pipeline drugs market research report outlays comprehensive information on the Leptin Receptor targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Leptin Receptor pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Metabolic Disorders, Non Malignant Disorders, Central Nervous System, and Oncology which include the indications Obesity, Lipodystrophy (Lipoatrophy), Benign Tumor, Sleep Disorders, Gastric Cancer, and Metastatic Melanoma. It also reviews key players involved in Leptin Receptor targeted therapeutics development with respective active and dormant or discontinued products.
The Leptin Receptor pipeline targets constitutes close to five molecules. Out of which, approximately five molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, and Preclinical stages are 1, 1, 1, and 2 respectively.
Leptin Receptor overview
Leptin receptor or LEP-R is a protein encoded by the LEPR gene. It acts as a receptor for hormone LEP/leptin. Upon binding it mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade. LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery increases basal metabolism, influences reproductive function, regulates pancreatic beta-cell function and insulin secretion, is pro-angiogenic and affects innate and adaptive immunity.
For a complete picture of Leptin Receptor’s drug pipeline, buy the report here.
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