The Kynurenine 3 Monooxygenase pipeline drugs market research report outlays comprehensive information on the Kynurenine 3 Monooxygenase targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Kynurenine 3 Monooxygenase pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Gastrointestinal, Infectious Disease, Immunology, and Metabolic Disorders which include the indications Pancreatitis, Viral Infections, Inflammation, and Metabolic Disorders. It also reviews key players involved in Kynurenine 3 Monooxygenase targeted therapeutics development with respective active and dormant or discontinued products.
The Kynurenine 3 Monooxygenase pipeline targets constitutes close to five molecules. Out of which, approximately five molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase I, Preclinical, and Discovery stages are 1, 3, and 1 respectively.
Kynurenine 3 Monooxygenase overview
Kynurenine 3-monooxygenase (KMO) is an enzyme that catalyzes the hydroxylation of L-kynurenine (L-Kyn) to produce 3-hydroxy-L-kynurenine (L-3OHKyn). KMO plays a crucial role in the synthesis of quinolinic acid, which is a neurotoxic compound that acts as an antagonist of N-methyl-D-aspartate (NMDA) receptors. Quinolinic acid has the potential to act as an endogenous inhibitor of NMDA receptor signaling in various biological processes, including axonal targeting, synaptogenesis, and apoptosis during brain development.
For a complete picture of Kynurenine 3 Monooxygenase’s drug pipeline, buy the report here.
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