The Kelch Like ECH Associated Protein 1 pipeline drugs market research report outlays comprehensive information on the Kelch Like ECH Associated Protein 1 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Kelch Like ECH Associated Protein 1 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Central Nervous System, Oncology, Genito Urinary System, and Gastrointestinal which include the indications Parkinson’s Disease, Friedreich Ataxia, Unspecified Cancer, Solid Tumor, Chronic Kidney Disease (Chronic Renal Failure), Diabetic Nephropathy, Oral Mucositis, and Inflammatory Bowel Disease. It also reviews key players involved in Kelch Like ECH Associated Protein 1 targeted therapeutics development with respective active and dormant or discontinued products.
The Kelch Like ECH Associated Protein 1 pipeline targets constitutes close to 19 molecules. Out of which, approximately 16 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Filing rejected/ Withdrawn, Phase III, Phase II, Phase I, Preclinical, and Discovery stages are 1, 1, 2, 2, 6, and 4 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 2, and 1 molecule.
Kelch Like ECH Associated Protein 1 overview
KEAP1 protein contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.
For a complete picture of Kelch Like ECH Associated Protein 1’s drug pipeline, buy the report here.
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